北京诺博莱德科技有限公司

GK125 ScienCell 人干细胞转录因子qPCR检测试剂盒，Human Stem Cell Transcription Factors qPCR Array Kit

ScienCell 研究实验室（ScienCell）是一家生物技术公司，其使命是实验和治疗用细胞和细胞相关产品的研究和发展。 ScienCell为研究界提供各种高质量的正常的人类和动物细胞，细胞培养基和试剂，培养基添加因子，细胞来源的RNA，cDNA和蛋白质。ScienCell的科学家们以改善生活质量，实现细胞的能力，打击人类退化性疾病为目的研究和开发各种细胞治疗策略。ScienCell总部设在美国加利福尼亚州圣地亚哥，公司成立于1999年。

北京诺博莱德作为ScienCell品牌的特约经销商，为客户提供，正规进口，保证原装正品，货期稳定，折扣好的服务标准。

GK125 ScienCell人干细胞转录因子qPCR检测试剂盒，Human Stem Cell Transcription Factors qPCR Array Kit，产品简介：

产品品牌： ScienCell

产品货号：GK125

产品名称：GK125 ScienCell人干细胞转录因子qPCR检测试剂盒，Human Stem Cell Transcription Factors qPCR Array Kit

产品规格：One 96-well plate, one 20ul reaction per well

GK125 ScienCell人干细胞转录因子qPCR检测试剂盒，Human Stem Cell Transcription Factors qPCR Array Kit， 产品说明：

ScienCell的GeneQuery™人类干细胞转录因子qPCR阵列试剂盒（GQH-SCT）调查了与干细胞维持和分化相关的88种转录因子。转录因子是通过结合基因组的特定区域（称为增强子或消音器）来调节靶基因转录水平的蛋白质。下面显示了如何根据其功能对基因进行分组的简要示例：   

多能性转录因子：NANOG、POU5F1、SOX2

胚胎发育：EOMES，FOXC2 / D3 / O1，HOXA9 / A10，KLF2 / 5，LIN28B，MAX，PITX2，SMAD1，TBX5，ZIC1

胚层形成和分化：FOXA2、GATA6、HAND1、ISL1、KLF4、SMAD2、SOX9

器官形态发生： EZH2， HOXA11/B3/B5/C9， MSX2， MYC， PAX5/8， VDR

血管生成： CDX2， JUN， NR2F2， RUNX1， WT1

造血和成骨： EGR3， ESR1， GATA1/2/3， GLI2， NFATC1， PAX9， RB1， SOX6， SP1， STAT1

神经干细胞维持和分化：ATF2、CREB1、FOSB、FOXO3、HES1、HOXD10、MCM2/7、MEF2C、NEUROD1/G1、OLIG1/2、PAX3/6、POU4F1、PPARG、SMAD3/4、SNAI1、STAT3

注意：所有基因名称都遵循人类基因组组织基因命名委员会（HGNC）的guanfang符号。

GeneQuery™ qPCR 芯片试剂盒采用 96 孔板格式的 qPCR 就绪，每个孔包含一个引物组，可以特异性识别并有效扩增靶基因的 cDNA。精心设计的引物确保：（i）qPCR分析中的最佳退火温度为65°C（含2 mM Mg2+，不含DMSO）;（ii）除非另有说明，否则引物组可识别靶基因的所有已知转录本变体;（iii）只有一个基因被扩增。每个引物组都已通过qPCR和熔解曲线分析和凝胶电泳进行了验证。

ScienCell's GeneQuery™ Human Stem Cell Transcription Factors qPCR Array Kit (GQH-SCT) surveys a panel of 88 transcription factors related to stem cell maintenance and differentiation. Transcription factors are proteins that can regulate target gene transcription level by binding to specific regions of the genome known as enhancers or silencers. Brief examples of how genes may be grouped according to their functions are shown below:     

·         Pluripotency transcription factors: NANOG, POU5F1, SOX2

·         Embryonic development: EOMES, FOXC2/D3/O1, HOXA9/A10, KLF2/5, LIN28B, MAX, PITX2, SMAD1, TBX5, ZIC1

·         Germ layer formation and differentiation: FOXA2, GATA6, HAND1, ISL1, KLF4, SMAD2, SOX9

·         Organ morphogenesis: EZH2, HOXA11/B3/B5/C9, MSX2, MYC, PAX5/8, VDR

·         Angiogenesis: CDX2, JUN, NR2F2, RUNX1, WT1

·         Hematopoiesis and osteogenesis: EGR3, ESR1, GATA1/2/3, GLI2, NFATC1, PAX9, RB1, SOX6, SP1, STAT1

·         Neural stem cell maintenance and differentiation: ATF2, CREB1, FOSB, FOXO3, HES1, HOXD10, MCM2/7, MEF2C, NEUROD1/G1, OLIG1/2, PAX3/6, POU4F1, PPARG, SMAD3/4, SNAI1, STAT3

Note: all gene names follow their official symbols by the Human Genome Organization Gene Nomenclature Committee (HGNC).

GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that can specifically recognize and efficiently amplify a target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+, and no DMSO); (ii) the primer set recognizes all known transcript variants of target gene, unless otherwise indicated; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis, and gel electrophoresis. 

基因查询™人类干细胞转录因子qPCR阵列板布局 *（8 个粗体和斜体控件）

注意：所有基因名称都遵循HGNC的guanfang符号

提示：基因选择可能会根据新的研究和开发进行更新

ScienCell基因表达分析产品订购信息：

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GK002   人类多能干细胞qPCR检测试剂盒，Human Pluripotent Stem Cell qPCR Array Kit

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GK010   人类黑素细胞发育和色素沉着qPCR检测试剂盒，Human Melanocyte Development & Pigmentation qPCR Array Kit

GK011   人类黑素细胞生物学qPCR检测试剂盒，Human Melanocyte Cell Biology qPCR Array Kit

GK013   人类星型胶质细胞转录因子qPCR检测试剂盒，Human Astrocyte Transcription Factors qPCR Array Kit

GK017   人血管生成qPCR检测试剂盒，Human Angiogenesis qPCR Array Kit

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GK019   人内皮细胞生物学qPCR检测试剂盒，Human Endothelial Cell Biology qPCR Array Kit

GK020   人B细胞受体信号通路qPCR检测试剂盒，Human B Cell Receptor Signaling Pathway qPCR Array Kit

GK021   人类T细胞受体信号通路qPCR检测试剂盒，Human T Cell Receptor Signaling Pathway qPCR Array Kit

GK022   人内吞作用qPCR检测试剂盒，Human Endocytosis qPCR Array Kit

GK023   人皮内细胞分化qPCR检测试剂盒，Human Endothelial Cell Differentiation qPCR Array Kit

GK024   人体剪切应力和机械传导qPCR检测试剂盒，Human Shear Stress and Mechanotransduction qPCR Array Kit

GK025   人类Notch信号通路qPCR检测试剂盒，uman Notch Signaling Pathway qPCR Array Kit

GK026   人类Wnt信号通路qPCR检测试剂盒，Human Wnt Signaling Pathway qPCR Array Kit

GK027   人类非经典Wnt信号通路qPCR检测试剂盒，Human Noncanonical Wnt Signaling Pathways qPCR Array Kit

GK028   人类Wnt信号靶基因qPCR检测试剂盒，Human Wnt Signaling Target Genes qPCR Array Kit

GK029   Human Tie2/Angpt信号qPCR检测试剂盒，Human Tie2/Angpt Signaling qPCR Array Kit

GK034   人肺纤维化qPCR检测试剂盒，Human Pulmonary Fibrosis qPCR Array Kit

GK035   人体缺氧反应qPCR检测试剂盒，Human Hypoxia Response qPCR Array Kit

GK036   人类HIF1信号响应qPCR检测试剂盒，Human HIF1 Signaling Response qPCR Array Kit

GK037   人巨噬细胞细胞生物学qPCR检测试剂盒，Human Macrophage Cell Biology qPCR Array Kit

GK038   人类吞噬作用qPCR检测试剂盒，Human Phagocytosis qPCR Array Kit

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GK040   人成纤维细胞生长因子信号通路qPCR检测试剂盒，Human Fibroblast Growth Factor Signaling Pathway qPCR Array Kit

GK041   人体皮肤伤口愈合qPCR检测试剂盒，Human Skin Wound Healing qPCR Array Kit

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GK073   人类小胶质细胞Sensome qPCR检测试剂盒，Human Microglial Sensome qPCR Array Kit

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GK079   人类软骨细胞生物学qPCR检测试剂盒，Human Chondrocyte Biology qPCR Array Kit

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GK081   人类周细胞生物学qPCR检测试剂盒，Human Pericyte Biology qPCR Array Kit

GK084   人体轴突导向qPCR检测试剂盒，Human Axon Guidance qPCR Array kit

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GK088   人VEGF信号通路qPCR检测试剂盒，Human VEGF Signaling Pathway qPCR Array Kit

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GK094   Human Mesenchymal Stem Cell Differentiation qPCR Array，Human Mesenchymal Stem Cell Differentiation qPCR Array Kit

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GK096   人类雪旺细胞生物学qPCR检测试剂盒，Human Schwann Cell Biology qPCR Array Kit

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GK117   人胸腺细胞发育标记qPCR检测试剂盒，Human Thymocyte Development Markers qPCR Array Kit

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